Which part of nephron of the human kidney is responsible for filtration of blood for excretion?

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NDA-II 2024 (GAT) Official Paper (Held On: 01 Sept, 2024)
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  1. Collecting duct
  2. Renal vein
  3. Ureter
  4. Bowman's capsule

Answer (Detailed Solution Below)

Option 4 : Bowman's capsule
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Detailed Solution

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The correct answer is Bowman's capsule

Concept:

  • The nephron is the functional unit of the kidney, responsible for filtering blood and forming urine.
  • The nephron consists of various parts, each with a specific function in the filtration and reabsorption process.
  • Components of the nephron are
    • Bowmans Capsule
    • Glomerulus
    • Proximal Convoluted tubule (PCT)
    • Loop of Henle
    • Distal convoluted tubule (DCT)
  • Bowman's capsule is a cup-like structure that encases the glomerulus, where the filtration of blood takes place.

F2 Utakarsha 25-10-21 Savita D2

Explanation:

  • Bowman's capsule is a cup-like sack at the beginning of the tubular component of a nephron in the mammalian kidney.
  • The blood gets filtered through 3 layers, i.e., the endothelium of glomerular blood vessels, the epithelium of Bowman’s capsule, and a basement membrane between these two layers.
  • The epithelial cells of Bowman’s capsule called podocytes are arranged in an intricate manner so as to leave some minute spaces called filtration slits or slit pores.
  • Blood is filtered so finely through these membranes, that almost all the constituents of the plasma except the proteins pass onto the lumen of the Bowman’s capsule.

Other Options:

  • Collecting duct: This part of the nephron is involved in the reabsorption of water and the concentration of urine.
  • Renal vein: The renal vein is responsible for carrying filtered blood away from the kidney back to the heart.
  • Ureter: The ureter is a tube that carries urine from the kidney to the bladder.
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