Given below are the list of plant derived alkaloids and their uses in modern medicine.

Alkaloids

Uses

A.

Caffeine

I.

Antineoplastic used to treat leukemia and other cancers

B.

Morphine

ii.

Traditional anti-malarial agent

C.

Quinine

iii.

Powerful narcotic analgesic

D.

Vincristine

iv.

Widely used central nervous system stimulant


Which one of the following options represents all correct matches?

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CSIR-UGC (NET) Life Science: Held on (6 June 2023 Shift 2)
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  1. A - (iii), B - (iv), C - (ii), D - (i)
  2. A - (iii), B - (iv), C - (i), D - (ii)
  3. A - (iv), B - (i), C - (iii), D - (ii)
  4. A - (iv), B - (iii), C - (ii), D - (i)

Answer (Detailed Solution Below)

Option 4 : A - (iv), B - (iii), C - (ii), D - (i)
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Detailed Solution

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The correct answer is Option 4 i.e.A - (iv), B - (iii), C - (ii), D - (i)

Key PointsA: Caffeine

  • Widely used central nervous system stimulant.
  • Caffeine is a drug that stimulates (increases the activity of) your brain and nervous system.
  • Caffeine is found in many drinks such as coffee, tea, soft drinks and energy drinks.
  • Chocolate also contains caffeine. Energy drinks often have more caffeine and sugar than soft drinks.

B: Morphine

  • Powerful narcotic analgesic.
  • Morphine is used to relieve moderate to severe pain.
  • Morphine extended-release tablets and capsules are only used to relieve severe (around-the-clock) pain that cannot be controlled by the use of other pain medications.

C: Quinine

  • Traditional anti-malarial agent.
  • Quinine is used alone or with other medications to treat malaria (a serious or life-threatening illness)
  • It is spread by mosquitos in certain parts of the world.
  • Quinine is in a class of medications called antimalarials.

D: Vincristine

  • Vincristine belongs to a group of drugs known as the vinca alkaloids.
  • Vinca alkaloids are organic compounds made up of carbon, hydrogen, nitrogen, and oxygen derived from the periwinkle plant.
  • These drugs block cell growth by stopping mitosis by interfering with microtubule polymerization.

Corrected table:

Alkaloids

Uses

A.

Caffeine

iv.

Widely used central nervous system stimulant

B.

Morphine

iii.

Powerful narcotic analgesic

C.

Quinine

ii.

Traditional anti-malarial agent

D.

Vincristine

i.

Antineoplastic used to treat leukemia and other cancers

Hence Option 4: A - (iv), B - (iii), C - (ii), D - (i) is correct 

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