Histones are enriched with -

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NEET 2025 Official Paper (Held On: 04 May, 2025)
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  1. Lysine & Arginine
  2. Leucine & Lysine  
  3. Phenylalanine & Leucine  
  4. Phenylalanine & Arginine 

Answer (Detailed Solution Below)

Option 1 : Lysine & Arginine
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CT 1: Botany (Cell:The Unit of Life)
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The correct answer is Lysine & Arginine

Expanation:

  • The nucleosome is the basic structural unit of chromatin in eukaryotic cells. It plays a critical role in the packaging of DNA into a compact, dense shape, which allows for efficient storage and regulation of genetic information.
  • A nucleosome consists of a segment of DNA wound around a core of histone proteins.
  • Histones are rich in the basic amino acid residues lysine and arginine. Both the amino acid residues carry positive charges in their side chains.
  • Histones are organised to form a unit of eight molecules called histone octamer.
  • The histone core around which DNA is wrapped is composed of eight histone molecules: two each of histone proteins H2A, H2B, H3, and H4.
  • The negatively charged DNA is wrapped around the positively charged histone octamer to form a structure called nucleosome
  • A typical nucleosome contains 200 bp of DNA helix.
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