Some of the spindle microtubules bind to the chromosomes in the special region of the centromere is called

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  1. kinesins
  2. kinetochore
  3. katanin
  4. profilins

Answer (Detailed Solution Below)

Option 2 : kinetochore
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The correct answer is kinetochore

Concept:

  • During cell division, the spindle microtubules play a crucial role in ensuring that chromosomes are properly segregated to the daughter cells.
  • The spindle apparatus is composed of microtubules that emanate from the centrosomes, and some of these microtubules attach to the chromosomes at a specific region called the kinetochore.
  • The kinetochore is a protein structure located at the centromere of each chromosome, which serves as the attachment site for spindle microtubules.

Explanation:

  • Kinesins: These are motor proteins that move along microtubule tracks and are involved in intracellular transport, but they do not specifically bind to chromosomes at the centromere.
  • Kinetochore: This is the correct answer. The kinetochore is a complex protein structure that assembles on the centromere of each chromosome during cell division. It serves as the attachment point for spindle microtubules, which are essential for the accurate segregation of chromosomes into daughter cells.
  • Katanin: This is a microtubule-severing protein that plays a role in microtubule dynamics but does not bind to the chromosomes at the centromere.
  • Profilins: These are actin-binding proteins that regulate the polymerization of actin filaments, and they are not involved in the attachment of spindle microtubules to chromosomes.
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